Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.89 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863598 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9ATSHRPOLB | |
| SCHEMBL4869603 | 0.92 | TSHR (0.95) | SMN1; SMN2NPC1RAB9ATSHRPOLB | |
| SCHEMBL4863867 | 0.92 | TSHR (0.95) | SMN1; SMN2NPC1RAB9ATSHRPOLB | |
| SCHEMBL4870617 | 0.92 | TSHR (0.95) | SMN1; SMN2NPC1RAB9ATSHRPOLB | |
| SCHEMBL4871280 | 0.90 | TSHR (0.92) | SMN1; SMN2NPC1RAB9ATSHRPOLB | |
| SCHEMBL1867264 | 0.81 | NPC1 (0.68) | SMN1; SMN2NPC1RAB9ATSHRPOLB | |
| SCHEMBL1865105 | 0.81 | NPC1 (0.68) | SMN1; SMN2NPC1RAB9ATSHRPOLB | |
| SCHEMBL7266739 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9ATSHRPOLB | |
| SCHEMBL7266518 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9ATSHRPOLB | |
| SCHEMBL4869962 | 0.80 | TSHR (0.74) | SMN1; SMN2NPC1RAB9ATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | claimed |
| EP-2493853-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2012-09-05 | — | — | EP | claimed |
| WO-2011051394-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2011-05-05 | — | — | WO | claimed |
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| US-20120263848-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-18 | — | — | US | disclosed |
| EP-2493853-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051394-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263848-A1 | Organic Compounds | OR10J3, CBR3, C9 | SMN1; SMN2 3112/4885NPC1 1550/4885RAB9A 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.