Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 20/20 | 0.73 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.73 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326309 | 0.95 | S1PR5 (0.81) | S1PR5S1PR1S1PR3 | |
| SCHEMBL327153 | 0.85 | S1PR5 (1.00) | S1PR5S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL326181 | 0.84 | S1PR5 (1.00) | S1PR5S1PR1S1PR3 | |
| SCHEMBL10265203 | 0.83 | S1PR5 (0.87) | S1PR5S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL325851 | 0.83 | S1PR5 (0.87) | S1PR5S1PR1S1PR3 | |
| SCHEMBL326270 | 0.82 | S1PR5 (0.77) | S1PR5S1PR1S1PR3 | |
| SCHEMBL325909 | 0.82 | S1PR5 (1.00) | S1PR5S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL326757 | 0.81 | S1PR5 (1.00) | S1PR5S1PR1S1PR3 | |
| SCHEMBL10265567 | 0.81 | S1PR5 (0.83) | S1PR5S1PR1S1PR3 | |
| SCHEMBL325672 | 0.81 | S1PR5 (0.91) | S1PR5S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144312-A1 | SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS | AbbVie B.V. (NL) | 2017-03-22 | — | — | EP | disclosed |