Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18657756 | 0.93 | EGFR (0.59) | EGFR | |
| SCHEMBL18563153 | 0.92 | EGFR (0.59) | EGFR | |
| SCHEMBL17196901 | 0.92 | EGFR (0.62) | EGFR | |
| SCHEMBL18657443 | 0.86 | EGFR (0.68) | EGFR | |
| SCHEMBL17196835 | 0.85 | EGFR (0.66) | EGFR | |
| SCHEMBL17196672 | 0.85 | EGFR (0.66) | EGFR | |
| SCHEMBL18657531 | 0.85 | EGFR (0.60) | EGFR | |
| SCHEMBL17196677 | 0.85 | EGFR (0.68) | EGFR | |
| SCHEMBL17196867 | 0.84 | EGFR (0.65) | EGFR | |
| SCHEMBL17196783 | 0.84 | EGFR (0.66) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144292-A1 | 2,3,4,6-TETRA-SUBSTITUTED BENZENE-1,5-DIAMINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICINAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD (US) | 2017-03-22 | — | — | EP | disclosed |