Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20694212 | 1.00 | KCNA5 (0.40) | KCNA5SLC6A2SLC6A4CYP1A2CHRM2 | |
| SCHEMBL12533650 | 0.91 | KCNA5 (0.38) | KCNA5SLC6A2SLC6A4CYP1A2CHRM2 | |
| SCHEMBL26023770 | 0.91 | KCNA5 (0.40) | KCNA5SLC6A2SLC6A4CYP1A2CHRM2 | |
| SCHEMBL18400269 | 0.88 | KCNA5 (0.45) | KCNA5SLC6A2SLC6A4CYP1A2CHRM2 | |
| SCHEMBL20465414 | 0.88 | KCNA5 (0.45) | KCNA5SLC6A2SLC6A4CYP1A2CHRM2 | |
| SCHEMBL25492608 | 0.84 | CYP3A4 (0.41) | KCNA5SLC6A2SLC6A4CYP1A2CHRM2 | |
| SCHEMBL22645178 | 0.81 | KCNA5 (0.38) | KCNA5SLC6A2SLC6A4CHRM2SCN1A | |
| SCHEMBL24959978 | 0.81 | KCNA5 (0.38) | KCNA5SLC6A2SLC6A4CHRM2SCN1A | |
| SCHEMBL18658742 | 0.80 | SLC6A2 (0.46) | KCNA5SLC6A2SLC6A4KDM4ESLC6A3 | |
| SCHEMBL13428369 | 0.80 | SLC6A2 (0.55) | SLC6A2SLC6A4CYP1A2CHRM2SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10222390-B2 | Near-infrared fluorescent sensors for biological amines | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170082645-A1 | NEAR-INFRARED FLUORESCENT SENSORS FOR BIOLOGICAL AMINES | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2017-03-23 | — | — | US | disclosed |