SCHEMBL18659986

SCHEMBL18659986

CCc1ccccc1-c1nc2ccccc2n1-c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.63
MAPK1 P28482 3/20 0.57
HTT P42858 1/20 0.57
RAB9A P51151 1/20 0.54
ESR1 P03372 4/20 0.51
ESR2 Q92731 4/20 0.51
GSR P00390 1/20 0.50
PRKACA P17612 1/20 0.48
RPS6KB1 P23443 1/20 0.48
GSK3B P49841 1/20 0.48
ROCK1 Q13464 1/20 0.48
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TSHR P16473 2/20 0.44
SLC22A12 Q96S37 1/20 0.44
USP2 O75604 1/20 0.44
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 3/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085156 0.85 RECQL (0.71) RECQLMAPK1HTTRAB9AESR1
SCHEMBL13926642 0.85 RECQL (0.56) RECQLMAPK1HTTRAB9AESR1
SCHEMBL12854005 0.84 RECQL (0.69) RECQLMAPK1HTTRAB9AESR1
SCHEMBL3473850 0.84 RECQL (0.69) RECQLMAPK1HTTRAB9AESR1
SCHEMBL4387592 0.84 RECQL (0.55) RECQLMAPK1HTTRAB9AESR1
SCHEMBL8010509 0.83 RECQL (0.64) RECQLMAPK1HTTRAB9AESR1
SCHEMBL26518519 0.81 KDM4E (0.54) MAPK1HTTRAB9AMEN1KMT2A
SCHEMBL31038155 0.81 RECQL (0.58) RECQLMAPK1HTTRAB9AESR1
SCHEMBL21742579 0.80 RECQL (0.61) RECQLMAPK1HTTRAB9AESR1
SCHEMBL13271460 0.80 POLB (0.45) RECQLMAPK1HTTRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3578564-A1 NOVEL HETEROLEPTIC IRIDIUM COMPLEXES Universal Display Corporation (US) 2019-12-11 EP disclosed
EP-2891659-B1 Organic Electroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-03-22 EP disclosed