Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.66 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.66 |
| ▸ | IGF1R | P08069 | 12/20 | 0.64 |
| ▸ | EGFR | P00533 | 4/20 | 0.64 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.64 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.64 |
| ▸ | BRAF | P15056 | 3/20 | 0.53 |
| ▸ | INSR | P06213 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1788724 | 0.94 | CDK19 (0.70) | CDK19ALKIGF1REGFRERBB2 | |
| SCHEMBL1786655 | 0.90 | CDK19 (0.67) | CDK19ALKIGF1REGFRERBB2 | |
| SCHEMBL1791459 | 0.90 | CDK19 (0.67) | CDK19ALKIGF1REGFRERBB2 | |
| SCHEMBL1790678 | 0.89 | IGF1R (0.80) | CDK19ALKIGF1REGFRERBB2 | |
| SCHEMBL1787518 | 0.89 | CDK19 (0.72) | CDK19ALKIGF1REGFRERBB2 | |
| SCHEMBL1789301 | 0.89 | CDK19 (0.70) | CDK19ALKIGF1REGFRERBB2 | |
| SCHEMBL1788368 | 0.89 | CDK19 (0.64) | CDK19ALKIGF1REGFRERBB2 | |
| SCHEMBL1790942 | 0.89 | CDK19 (0.64) | CDK19ALKIGF1REGFRERBB2 | |
| SCHEMBL1791218 | 0.88 | IGF1R (0.68) | CDK19ALKIGF1REGFRERBB2 | |
| SCHEMBL1789462 | 0.88 | CDK19 (0.65) | CDK19ALKIGF1REGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496574-A1 | IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION | Abbott Laboratories (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011053476-A1 | IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | WO | disclosed |