Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 16/20 | 0.49 |
| ▸ | POLA1 | P09884 | 1/20 | 0.49 |
| ▸ | POLG | P54098 | 1/20 | 0.49 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24114395 | 0.94 | POLB (0.52) | POLBHPRT1POLA1POLGPNP | |
| SCHEMBL17617327 | 0.88 | POLB (0.51) | POLBHPRT1POLA1POLGPNP | |
| SCHEMBL17617645 | 0.88 | POLB (0.51) | POLBHPRT1POLA1POLGPNP | |
| SCHEMBL24792218 | 0.88 | POLB (0.51) | POLBHPRT1POLA1POLGPNP | |
| SCHEMBL18665426 | 0.86 | POLB (0.57) | POLBHPRT1POLA1POLGPNP | |
| SCHEMBL23394755 | 0.85 | HPRT1 (0.51) | POLBHPRT1POLA1POLGPNP | |
| SCHEMBL23394746 | 0.85 | HPRT1 (0.51) | POLBHPRT1POLA1POLGPNP | |
| SCHEMBL14621723 | 0.85 | POLB (0.52) | POLBHPRT1POLA1POLGPNP | |
| SCHEMBL17617329 | 0.84 | POLB (0.53) | POLBHPRT1POLA1POLGPNP | |
| SCHEMBL17617646 | 0.84 | POLB (0.53) | POLBHPRT1POLA1POLGPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048956-A1 | NUCLEOTIDE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-23 | — | — | WO | disclosed |