Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13813121 | 0.79 | MAPK1 (0.60) | MEN1KMT2AMAPK1 | |
| SCHEMBL18627852 | 0.79 | MAPK1 (0.60) | MEN1KMT2AMAPK1 | |
| SCHEMBL18929646 | 0.78 | MAPK1 (0.62) | MEN1KMT2AMAPK1 | |
| SCHEMBL20016515 | 0.78 | MAPK1 (0.62) | MEN1KMT2AMAPK1 | |
| SCHEMBL23516631 | 0.77 | MAPK1 (0.51) | POLBL3MBTL1MEN1KMT2AGALR3 | |
| SCHEMBL15919164 | 0.74 | MAPK1 (0.35) | MEN1KMT2AMAPK1OGA | |
| SCHEMBL22559767 | 0.73 | MAPK1 (0.55) | MEN1KMT2AMAPK1CHRM1OGA | |
| SCHEMBL19871871 | 0.72 | MAPK1 (0.58) | POLBMEN1KMT2AMAPK1 | |
| SCHEMBL23332465 | 0.71 | MAPK1 (0.37) | POLBL3MBTL1MEN1KMT2AGALR3 | |
| SCHEMBL25669768 | 0.71 | MAPK1 (0.43) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048620-A1 | POLYNUCLEOTIDE AGENTS TARGETING PATATIN-LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3 (PNPLA3) AND METHODS OF USE THEREOF | ALNYLAM PHARMACEUTICALS, INC. (US) | 2017-03-23 | — | — | WO | disclosed |