Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080118 | 0.84 | MAPT (0.53) | HPGDMAPTLMNAVCAM1POLB | |
| SCHEMBL18381838 | 0.82 | HPGD (0.58) | HPGDMAPTLMNAVCAM1POLB | |
| SCHEMBL17080233 | 0.82 | HPGD (0.53) | HPGDMAPTLMNAVCAM1POLB | |
| SCHEMBL17080222 | 0.81 | HPGD (0.54) | HPGDMAPTLMNAVCAM1POLB | |
| SCHEMBL17080227 | 0.81 | HPGD (0.54) | HPGDMAPTLMNAVCAM1POLB | |
| SCHEMBL17080225 | 0.79 | SLC6A2 (0.56) | HPGDMAPTLMNAVCAM1POLB | |
| SCHEMBL17085945 | 0.78 | HPGD (0.54) | HPGDMAPTLMNAVCAM1POLB | |
| SCHEMBL30610315 | 0.78 | MAPT (0.58) | HPGDMAPTLMNAVCAM1POLB | |
| SCHEMBL16430875 | 0.78 | MAPT (0.58) | HPGDMAPTLMNAVCAM1POLB | |
| SCHEMBL17080117 | 0.77 | HPGD (0.56) | HPGDMAPTLMNAVCAM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048950-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |