SCHEMBL18669409

SCHEMBL18669409

CC(C)CC1NCCc2c1[nH]c1cc(F)ccc21

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 16/20 0.59
HTR2C P28335 15/20 0.59
MAPKAPK2 P49137 1/20 0.44
GRIN2B Q13224 1/20 0.44
HTR2B P41595 2/20 0.44
KDM4E B2RXH2 1/20 0.43
PSMD14 O00487 1/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23116665 0.90 HTR2A (0.73) HTR2AHTR2CMAPKAPK2HTR2B
SCHEMBL23138523 0.86 HTR2B (0.47) HTR2AHTR2CGRIN2BHTR2BKDM4E
SCHEMBL23116663 0.85 HTR2A (0.60) HTR2AHTR2CMAPKAPK2GRIN2B
Hydrochloric Acid SCHEMBL23116673 0.85 HTR2B (0.49) HTR2AHTR2CGRIN2BHTR2BKDM4E
SCHEMBL23116677 0.83 MAPT (0.66) HTR2AHTR2CMAPKAPK2HTR2BKDM4E
SCHEMBL18669422 0.82 GRIN2B (0.65) HTR2AHTR2CMAPKAPK2GRIN2B
SCHEMBL23116654 0.81 HTR2A (0.58) HTR2AHTR2CMAPKAPK2HTR2BKDM4E
SCHEMBL23116678 0.79 HTR2B (0.58) HTR2AHTR2CHTR2B
SCHEMBL14917262 0.78 HTR2A (0.55) HTR2AHTR2CHTR2B
SCHEMBL10086583 0.78 HTR2A (0.75) HTR2AHTR2CMAPKAPK2HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630512-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2026-05-19 US disclosed
EP-3600451-B1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2025-12-24 EP disclosed
US-12202799-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2025-01-21 US disclosed
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2024-12-12 US disclosed
US-20240307359-A1 METHOD OF SCREENING FOR AGENTS FOR DIFFERENTIATING STEM CELLS MINERVA BIOTECHNOLOGIES CORP (US) 2024-09-19 US disclosed
US-11931347-B2 Method of screening for agents for differentiating stem cells MINERVA BIOTECHNOLOGIES CORPORATION (US) 2024-03-19 US disclosed
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2022-08-04 US disclosed
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2022-08-04 US disclosed
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MINERVA BIOTECHNOLOGIES CORPORATION 2021-09-30 US disclosed
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MINERVA BIOTECHNOLOGIES CORPORATION 2021-09-30 US disclosed
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2021-03-25 US disclosed
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2021-03-25 US disclosed
US-20180263964-A1 METHOD OF SCREENING FOR AGENTS FOR DIFFERENTIATING STEM CELLS MINERVA BIOTECHNOLOGIES CORPORATION (US) 2018-09-20 US disclosed
EP-3352566-A2 METHOD OF SCREENING FOR AGENTS FOR DIFFERENTIATING STEM CELLS Minerva Biotechnologies Corporation (US) 2018-08-01 EP disclosed
WO-2017053886-A2 METHOD OF SCREENING FOR AGENTS FOR DIFFERENTIATING STEM CELLS MINERVA BIOTECHNOLOGIES CORPORATION (US) 2017-03-30 WO disclosed
WO-2017053886-A2 METHOD OF SCREENING FOR AGENTS FOR DIFFERENTIATING STEM CELLS MINERVA BIOTECHNOLOGIES CORPORATION (US) 2017-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180263964-A1 METHOD OF SCREENING FOR AGENTS FOR DIFFERENTIATING STEM CELLS MCL1, CRABP2, MYADM HTR2A 4495/4885HTR2C 4518/4885MAPKAPK2 322/4885
US-11931347-B2 Method of screening for agents for differentiating stem cells MCL1, CRABP2, MYADM HTR2A 4495/4885HTR2C 4518/4885MAPKAPK2 322/4885
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MCL1, CD44, EPCAM HTR2A 4615/4885HTR2C 4566/4885MAPKAPK2 719/4885
US-20240307359-A1 METHOD OF SCREENING FOR AGENTS FOR DIFFERENTIATING STEM CELLS MCL1, CRABP2, MYADM HTR2A 4495/4885HTR2C 4518/4885MAPKAPK2 322/4885
US-12202799-B2 Agents for differentiating stem cells and treating cancer MCL1, CD44, CRABP2 HTR2A 4440/4885HTR2C 4453/4885MAPKAPK2 565/4885
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 HTR2A 4440/4885HTR2C 4453/4885MAPKAPK2 565/4885
US-12630512-B2 Agents for differentiating stem cells and treating cancer MCL1, POU2F1, NES HTR2A 3307/4885HTR2C 1923/4885MAPKAPK2 3550/4885
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 HTR2A 4440/4885HTR2C 4453/4885MAPKAPK2 565/4885
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 HTR2A 4440/4885HTR2C 4453/4885MAPKAPK2 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.