⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029257 | 1.00 | — | — | |
| SCHEMBL186707 | 1.00 | — | — | |
| SCHEMBL11215493 | 0.97 | — | — | |
| Magnesium SCHEMBL30497669 | 0.97 | AKR1B1 (0.43) | — | |
| SCHEMBL31558661 | 0.94 | — | — | |
| SCHEMBL3881630 | 0.75 | — | — | |
| SCHEMBL1472445 | 0.75 | — | — | |
| SCHEMBL2318381 | 0.73 | AKR1B1 (0.40) | — | |
| SCHEMBL3202899 | 0.73 | AKR1B1 (0.40) | — | |
| SCHEMBL127505 | 0.72 | SLC6A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167109-A1 | Aminopiperidine Amides, Derivatives, Compositions, and Uses Related to CXCR4 Modulation | UNIV EMORY (US) | 2023-06-01 | — | — | US | claimed |
| WO-2021217143-A1 | AMINOPIPERIDINE AMIDES, DERIVATIVES, COMPOSITIONS, AND USES RELATED TO CXCR4 MODULATION | EMORY UNIVERSITY (US) | 2021-10-28 | — | — | WO | claimed |
| US-20140309192-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC, | 2014-10-16 | — | — | US | claimed |
| CN-104105691-A | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC | 2014-10-15 | — | — | CN | claimed |
| EP-2776407-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2014-09-17 | — | — | EP | claimed |
| WO-2013070657-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2013-05-16 | — | — | WO | claimed |
| US-8071625-B2 | E.g., [(1-(2-aminoacetyl)-4-{N-[(3-fluoro-2-methylphenyl)methyl]carbamoyl}(4-piperidyl))methoxy]-N-(4-ethylphenyl)carboxamide; smooth muscle myosin or non-muscle myosin modulator; hypotensive agent; asthma, COPD, bronchoconstrictive disease, glaucoma, pre-menstrual cramps, erectile dysfunction | CYTOKINETICS, INC. (US) | 2011-12-06 | — | — | US | claimed |
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | claimed |
| EP-1240154-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | claimed |
| US-7157585-B2 | Serine protease inhibitors | TULARIK LIMITED (GB) | 2007-01-02 | — | — | US | claimed |
| US-20010016591-A1 | Fungicidal active compound combinations | STENZEL KLAUS (DE) | 2001-08-23 | — | — | US | claimed |
| WO-2001044226-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-06-21 | — | — | WO | claimed |
| EP-0707792-B1 | Fungicidal combinations of active agents | BAYER AG (DE) | 1999-01-20 | — | — | EP | claimed |
| US-5814138-A | COMPRISING AQUEOUS LIQUID VEHICLE, SELECTED COSOLVENT OPTIONALLY INCLUDING ETHYLENE GLYCOL, COLORANT, AMMONIUM BROMIDE | XEROX CORPORATION (US) | 1998-09-29 | — | — | US | claimed |
| EP-0602914-B1 | Ink compositions for ink jet printing | XEROX CORP (US) | 1997-11-12 | — | — | EP | claimed |
| CN-1132591-A | Fungicidal active substance mixtures | BAYER AG (DE) | 1996-10-09 | — | — | CN | claimed |
| EP-0707792-A1 | Fungicidal combinations of active agents | BAYER AG (DE) | 1996-04-24 | — | — | EP | claimed |
| US-5300143-A | Water soluble dye, sulfone, and amide or cyclic amine | XEROX CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| US-5223026-A | Mixture of water and cyclic amides or cyclic esters and coloring material as ink for thermal printing | XEROX CORPORATION (US) | 1993-06-29 | — | — | US | claimed |
| US-4529822-A | Process for the preparation of formamide compounds | TEXACO, INC. (US) | 1985-07-16 | — | — | US | claimed |