Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653508 | 0.87 | HDAC1 (0.76) | HDAC1HDAC3HDAC2 | |
| SCHEMBL4581935 | 0.87 | HDAC1 (0.79) | HDAC1HDAC3HDAC2KCNH2 | |
| SCHEMBL18670965 | 0.86 | HDAC1 (0.65) | HDAC1HDAC3HDAC2KCNH2 | |
| SCHEMBL18670977 | 0.86 | HDAC1 (0.65) | HDAC1HDAC3HDAC2KCNH2 | |
| SCHEMBL18670954 | 0.85 | HDAC1 (0.77) | HDAC1HDAC3HDAC2KCNH2 | |
| SCHEMBL4578711 | 0.84 | HDAC1 (0.84) | HDAC1HDAC3HDAC2KCNH2 | |
| SCHEMBL4580198 | 0.83 | HDAC1 (0.82) | HDAC1HDAC3HDAC2KCNH2 | |
| SCHEMBL4579434 | 0.83 | HDAC1 (0.70) | HDAC1HDAC3HDAC2KCNH2 | |
| SCHEMBL2137319 | 0.82 | HDAC1 (0.76) | HDAC1HDAC3HDAC2 | |
| SCHEMBL1065833 | 0.82 | ABCB1 (0.73) | HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603950-B1 | Compounds of imaging agent with HDAC inhibitor for treatment of Alzheimer syndrome and method of synthesis thereof | INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2017-03-28 | — | — | US | disclosed |
| US-9603950-B1 | Compounds of imaging agent with HDAC inhibitor for treatment of Alzheimer syndrome and method of synthesis thereof | INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2017-03-28 | — | — | US | disclosed |