Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 9/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634741 | 0.90 | TLR4 (0.65) | TLR4MRGPRX1LMNAKMT2AHRH1 | |
| SCHEMBL1872797 | 0.89 | TLR4 (0.62) | TLR4NPSR1MRGPRX1LMNAKMT2A | |
| SCHEMBL15146253 | 0.89 | TLR4 (0.62) | TLR4NPSR1MRGPRX1LMNAKMT2A | |
| SCHEMBL1863349 | 0.89 | TLR4 (0.62) | TLR4NPSR1MRGPRX1LMNAKMT2A | |
| SCHEMBL1863586 | 0.89 | TLR4 (0.62) | TLR4NPSR1MRGPRX1LMNAKMT2A | |
| SCHEMBL4144992 | 0.89 | TLR4 (0.46) | TLR4MRGPRX1LMNAKMT2ATP53 | |
| SCHEMBL1865243 | 0.89 | TLR4 (0.68) | TLR4NPSR1MRGPRX1LMNAKMT2A | |
| SCHEMBL1863271 | 0.88 | TLR4 (0.65) | TLR4NPSR1MRGPRX1LMNAKMT2A | |
| SCHEMBL12634733 | 0.88 | TLR4 (0.61) | TLR4NPSR1MRGPRX1LMNAKMT2A | |
| SCHEMBL1863576 | 0.87 | TLR4 (0.68) | TLR4NPSR1MRGPRX1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935835-B2 | Substituted cycloalkene derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-03 | — | — | US | disclosed |