Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.69 |
| ▸ | HTR2A | P28223 | 11/20 | 0.69 |
| ▸ | HTR1A | P08908 | 11/20 | 0.69 |
| ▸ | DRD3 | P35462 | 8/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.69 |
| ▸ | HTR2B | P41595 | 2/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.69 |
| ▸ | DRD1 | P21728 | 2/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.69 |
| ▸ | HTR7 | P34969 | 2/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18673182 | 0.85 | HTR2B (0.79) | DRD2HTR2AHTR1ADRD3ADRA2C | |
| SCHEMBL16804115 | 0.85 | HTR2B (0.79) | DRD2HTR2AHTR1ADRD3ADRA2C | |
| SCHEMBL31554976 | 0.85 | HTR2B (0.79) | DRD2HTR2AHTR1ADRD3ADRA2C | |
| SCHEMBL12620235 | 0.85 | HTR2B (0.81) | DRD2HTR2AHTR1ADRD3ADRA2C | |
| SCHEMBL12653555 | 0.85 | HTR2B (0.81) | DRD2HTR2AHTR1ADRD3ADRA2C | |
| SCHEMBL12620194 | 0.85 | HTR2B (0.81) | DRD2HTR2AHTR1ADRD3ADRA2C | |
| SCHEMBL12653557 | 0.85 | HTR2B (0.81) | DRD2HTR2AHTR1ADRD3ADRA2C | |
| SCHEMBL12653144 | 0.85 | HTR2B (0.81) | DRD2HTR2AHTR1ADRD3ADRA2C | |
| SCHEMBL12620197 | 0.85 | HTR2B (0.81) | DRD2HTR2AHTR1ADRD3ADRA2C | |
| SCHEMBL12620231 | 0.85 | HTR2B (0.81) | DRD2HTR2AHTR1ADRD3ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9606132-B2 | Methods of monitoring adherence to lurasidone therapy | AMERITOX, LTD. (US) | 2017-03-28 | — | — | US | disclosed |