Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 18/20 | 0.54 |
| ▸ | PKD1 | P98161 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18888203 | 1.00 | MAP3K14 (0.54) | MAP3K14PKD1MEN1KMT2A | |
| SCHEMBL18673456 | 0.90 | MAP3K14 (0.67) | MAP3K14PKD1 | |
| SCHEMBL16532371 | 0.81 | MAP3K14 (0.82) | MAP3K14PKD1 | |
| SCHEMBL18673457 | 0.78 | MAP3K14 (0.59) | MAP3K14PKD1 | |
| SCHEMBL16532694 | 0.75 | MAP3K14 (0.82) | MAP3K14PKD1 | |
| SCHEMBL16532432 | 0.74 | MAP3K14 (0.83) | MAP3K14PKD1 | |
| SCHEMBL16532501 | 0.74 | MAP3K14 (0.83) | MAP3K14PKD1 | |
| SCHEMBL16532372 | 0.73 | MAP3K14 (0.44) | MAP3K14MEN1KMT2A | |
| SCHEMBL16532531 | 0.73 | MAP3K14 (0.83) | MAP3K14PKD1 | |
| SCHEMBL16532587 | 0.72 | MAP3K14 (0.69) | MAP3K14PKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605005-B2 | Alkynyl alcohols and methods of use | GENENTECH, INC. (US) | 2017-03-28 | — | — | US | disclosed |