Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.76 |
| ▸ | PKD1 | P98161 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18673445 | 0.90 | MAP3K14 (0.75) | MAP3K14PKD1 | |
| SCHEMBL16516964 | 0.87 | MAP3K14 (1.00) | MAP3K14PKD1 | |
| SCHEMBL16516963 | 0.87 | MAP3K14 (1.00) | MAP3K14PKD1 | |
| SCHEMBL18888015 | 0.83 | MAP3K14 (0.74) | MAP3K14 | |
| SCHEMBL18888234 | 0.80 | MAP3K14 (0.75) | MAP3K14 | |
| SCHEMBL17920957 | 0.79 | MAP3K14 (0.83) | MAP3K14PKD1 | |
| SCHEMBL16517416 | 0.77 | MAP3K14 (1.00) | MAP3K14PKD1 | |
| SCHEMBL16517418 | 0.77 | MAP3K14 (1.00) | MAP3K14PKD1 | |
| SCHEMBL18888121 | 0.77 | MAP3K14 (0.69) | MAP3K14 | |
| SCHEMBL18888119 | 0.76 | MAP3K14 (0.77) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605005-B2 | Alkynyl alcohols and methods of use | GENENTECH, INC. (US) | 2017-03-28 | — | — | US | disclosed |