Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28633922 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| Bromide SCHEMBL29140475 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| Bromide SCHEMBL29140481 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| Bromide SCHEMBL29140476 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| Bromide SCHEMBL29140477 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| Bromide SCHEMBL28635420 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| Bromide SCHEMBL8196037 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| Bromide SCHEMBL3630565 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| Bromide SCHEMBL29140485 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 | |
| Bromide SCHEMBL27096505 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702436-A | Complexing agent with water reducing and mud inhibiting effects and preparation method thereof | 山东高速城乡发展集团有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-117364482-A | Plant fiber crease-resistant finishing agent, crease-resistant fabric and preparation method of crease-resistant fabric | 中山易必固电子束科技有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-117364483-A | Non-release composite antibacterial material, antibacterial fabric and preparation method thereof | 中山易必固电子束科技有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-113402971-B | Glass bead filled silicone gel anti-fouling bacteriostatic coating and preparation method and application thereof | 浙江大学衢州研究院 | 2022-04-05 | — | — | CN | claimed |
| CN-113337207-B | Nano-reinforced environment-friendly organic silicon antifouling antibacterial coating and preparation method and application thereof | 浙江大学衢州研究院 | 2022-04-05 | — | — | CN | claimed |
| CN-113402971-A | Glass bead filled silicone gel anti-fouling bacteriostatic coating and preparation method and application thereof | 浙江大学衢州研究院 | 2021-09-17 | — | — | CN | claimed |
| CN-113337207-A | Nano-reinforced environment-friendly organic silicon antifouling antibacterial coating and preparation method and application thereof | 浙江大学衢州研究院 | 2021-09-03 | — | — | CN | claimed |
| CN-106188556-B | Poly carboxylic acid modified carboxylic acid halides is grafted the method that compound side chain prepares cement water reducing agent | 北京工业大学 | 2019-04-05 | — | — | CN | claimed |
| CN-106188557-B | The method of unsaturated halogenated hydrocarbons copolymerized grafting cationic side chain preparation highly resistance chamotte mould polycarboxylate dispersant | 北京工业大学 | 2019-04-05 | — | — | CN | claimed |
| CN-106084243-B | The method that backbone modification isocyanates grafted cation side chain prepares polycarboxylate water-reducer | 北京工业大学 | 2019-03-22 | — | — | CN | claimed |
| CN-106380554-A | Preparation method of ester type viscosity reduction type polycarboxylate superplasticizer | 科之杰新材料集团有限公司 | 2017-02-08 | — | — | CN | claimed |
| CN-106188558-A | The method preparing cement water reducing agent for monomer with p styrene sulfonic acid salt | 北京工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106188557-A | The method that unsaturated halogenated hydrocarbons copolymerized grafting cationic side chain prepares high anti-chamotte mould polycarboxylate dispersant | 北京工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106188556-A | The method that cement water reducing agent prepared by the compound side chain of poly carboxylic acid modified carboxylic acid halides grafting | 北京工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106188428-A | The method of benzenesulfonic acid esters surface-active macromonomer copolyreaction synthesis high performance water reducing agent of polyocarboxy acid | 北京工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106117450-A | Method based on Hoffmann rearrangement reaction synthesizing cationic type polycarboxylate water-reducer | 北京工业大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106117564-A | A kind of preparation method of the height anti-chamotte mould cement dispersants of graft esterification cationic side chain | 北京工业大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106117468-A | The preparation method of the height anti-chamotte mould cement water reducing agent of graft copolymerization cationic side chain | 北京工业大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106117461-A | Thiazolinyl alcoholysis of acyl chloride prepares the method for polymeric monomer synthesis polycarboxylate water-reducer | 北京工业大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106084243-A | The method that polycarboxylate water-reducer prepared by backbone modification isocyanates grafted cation side chain | 北京工业大学 | 2016-11-09 | — | — | CN | claimed |