SCHEMBL18677237

SCHEMBL18677237

CN(C)c1ccc2c(c1)OC1=CC(C)(N(C)C)C=CC1=C2c1ccc(C(=O)NCCNC(=O)C(F)(F)F)cc1C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ F7 P08709 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18365334 0.86 P2RY6 (0.39) F7
SCHEMBL19275375 0.83 HDAC1 (0.35) —
SCHEMBL18677252 0.80 — —
SCHEMBL15159890 0.80 KMT2A (0.30) —
SCHEMBL16491631 0.79 USP2 (0.34) —
SCHEMBL18365336 0.76 — —
SCHEMBL16518794 0.71 TSHR (0.34) —
SCHEMBL18441261 0.70 KMT2A (0.31) —
SCHEMBL15031010 0.69 SMN1; SMN2 (0.38) —
SCHEMBL18503779 0.66 SLC16A3 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170087258-A1 TCO CONJUGATES AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2017-03-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170087258-A1 TCO CONJUGATES AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS FCGR2A, PAICS, CD47 F7 2969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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