Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918257 | 0.87 | POLB (0.46) | POLBEPHX1DUTDPP4HTT | |
| SCHEMBL18677728 | 0.85 | EPHX1 (0.44) | POLBEPHX1DUTDPP4HTT | |
| SCHEMBL20635863 | 0.84 | POLB (0.44) | POLBEPHX1DUTDPP4HTT | |
| SCHEMBL12949585 | 0.83 | POLB (0.31) | POLBDPP4 | |
| SCHEMBL14877799 | 0.82 | — | — | |
| SCHEMBL18677681 | 0.82 | POLB (0.37) | POLBEPHX1HTTMEN1MAPT | |
| SCHEMBL25064237 | 0.80 | POLB (0.37) | POLBEPHX1 | |
| SCHEMBL8279456 | 0.79 | POLB (0.43) | POLBEPHX1DUTHTTSMN1; SMN2 | |
| SCHEMBL13918255 | 0.78 | POLB (0.40) | POLBEPHX1DUTDPP4HTT | |
| SCHEMBL18677700 | 0.78 | POLB (0.34) | POLBEPHX1HTTMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637705-B1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | KING S COLLEGE LONDON (GB) | 2017-03-29 | — | — | EP | disclosed |