SCHEMBL18680477

SCHEMBL18680477

CC1(C)c2ccccc2N(c2ccc(-c3nc4cc5c(cc4s3)nc(-c3ccccc3)n5-c3ccccc3)cc2)c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
SMN1; SMN2 Q16637 6/20 0.35
PKM P14618 3/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
KMT2A Q03164 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
KDM4E B2RXH2 4/20 0.34
MAPT P10636 4/20 0.34
ALDH1A1 P00352 2/20 0.34
GLA P06280 2/20 0.34
GAA P10253 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 1/20 0.34
SIRT2 Q8IXJ6 2/20 0.34
SIRT1 Q96EB6 2/20 0.34
APP P05067 5/20 0.33
NFKB1 P19838 2/20 0.33
NFKB2 Q00653 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17283290 0.99 SMN1; SMN2 (0.36) ESR1ESR2SMN1; SMN2PKMNPC1
SCHEMBL17283324 0.90 ESR1 (0.41) ESR1ESR2SMN1; SMN2PKMNPC1
SCHEMBL17283294 0.89 NPC1 (0.41) ESR1ESR2SMN1; SMN2PKMNPC1
SCHEMBL17283230 0.89 ESR1 (0.43) ESR1ESR2KMT2AMAPTALDH1A1
SCHEMBL17283275 0.88 SMN1; SMN2 (0.43) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL17283277 0.88 ESR1 (0.41) ESR1ESR2SMN1; SMN2RAB9ANPSR1
SCHEMBL17283327 0.87 ESR1 (0.37) ESR1ESR2SMN1; SMN2PKMNPC1
SCHEMBL17283212 0.86 SMN1; SMN2 (0.45) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL17283295 0.85 SMN1; SMN2 (0.37) ESR1ESR2SMN1; SMN2PKMNPC1
SCHEMBL17283326 0.85 ESR1 (0.37) ESR1ESR2SMN1; SMN2PKMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2020-08-13 US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 ESR1 99/4885ESR2 692/4885SMN1; SMN2 2504/4885
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, TEAD2, TEAD4 ESR1 99/4885ESR2 692/4885SMN1; SMN2 2504/4885
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 ESR1 99/4885ESR2 692/4885SMN1; SMN2 2504/4885
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 ESR1 99/4885ESR2 692/4885SMN1; SMN2 2504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.