SCHEMBL1868142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1866492	0.78	KMT2A (0.57)	ALDH1A1CYP3A4CYP2D6CYP2C9RECQL
	SCHEMBL1865443	0.78	KMT2A (0.60)	ALDH1A1CYP3A4CYP2C9KMT2AGAA
	SCHEMBL1864666	0.78	KMT2A (0.60)	ALDH1A1CYP3A4KMT2AGAAMEN1
	SCHEMBL13679209	0.76	GAA (0.58)	ALDH1A1CYP2C9KMT2AGAAMEN1
	SCHEMBL1865490	0.76	GAA (0.58)	ALDH1A1CYP2C9KMT2AGAAMEN1
	SCHEMBL22408118	0.75	KMT2A (0.69)	ALDH1A1CYP3A4KMT2AGAAMEN1
	SCHEMBL6655913	0.75	KMT2A (0.69)	ALDH1A1CYP3A4KMT2AGAAMEN1
	SCHEMBL22408180	0.74	KMT2A (0.67)	ALDH1A1CYP3A4KMT2AGAAMEN1
	SCHEMBL14082502	0.73	KMT2A (0.51)	ALDH1A1CYP3A4KMT2AGAAMEN1
	SCHEMBL25983198	0.73	KMT2A (0.70)	ALDH1A1CYP3A4KMT2AGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.