Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.47 |
| ▸ | HTR2B | P41595 | 16/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013379 | 0.85 | HTR2C (0.65) | HTR2CHTR2BHTR6HTR2A | |
| SCHEMBL2016843 | 0.82 | HTR2C (0.46) | HTR2CHTR2BHTR6HTR2A | |
| SCHEMBL2015345 | 0.82 | HTR2C (0.46) | HTR2CHTR2BHTR2A | |
| SCHEMBL2020073 | 0.80 | HTR2C (0.52) | HTR2CHTR2BHTR2A | |
| SCHEMBL2017961 | 0.79 | HTR2C (0.49) | HTR2CHTR2BHTR2A | |
| SCHEMBL2016564 | 0.78 | HTR2C (0.47) | HTR2CHTR2BHTR2A | |
| SCHEMBL2017888 | 0.78 | HTR2C (0.47) | HTR2CHTR2BHTR2A | |
| SCHEMBL2578585 | 0.78 | HTR2C (0.47) | HTR2CHTR2BHTR2A | |
| SCHEMBL2020850 | 0.78 | HTR2C (0.46) | HTR2CHTR2BHTR2A | |
| SCHEMBL2015968 | 0.77 | HTR2C (0.62) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150607-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | AbbVie Inc. (US) | 2017-04-05 | — | — | EP | disclosed |