SCHEMBL18689461

SCHEMBL18689461

Cc1ccc2c3ccccc3n(-c3ccc(-c4ccc5ccccc5c4)cc3)c2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40
TUBA1A Q71U36 1/20 0.40
TUBA1C Q9BQE3 1/20 0.40
TUBB6 Q9BUF5 1/20 0.40
TUBB2B Q9BVA1 1/20 0.40
TUBB1 Q9H4B7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10023308 0.91 KDM4E (0.47) CYP2A6TDP1KDM4EATML3MBTL1
SCHEMBL19500807 0.90 MAPK10 (0.42) CYP2A6TDP1KDM4EATML3MBTL1
SCHEMBL12699650 0.90 KDM4E (0.48) KDM4EATML3MBTL1TUBB4ATUBB
SCHEMBL13957177 0.90 KDM4E (0.52) KDM4EATML3MBTL1ALDH1A1CYP2C9
SCHEMBL4406988 0.90 KDM4E (0.52) KDM4EATML3MBTL1ALDH1A1CYP2C9
SCHEMBL19130036 0.89 PIK3CD (0.42) CYP2A6TDP1KDM4EATML3MBTL1
SCHEMBL13829477 0.89 CYP2A6 (0.46) CYP2A6TDP1KDM4EATML3MBTL1
SCHEMBL26226195 0.89 KDM4E (0.44) CYP2A6TDP1KDM4EATML3MBTL1
SCHEMBL15040943 0.88 CYP2A6 (0.48) CYP2A6TDP1KDM4EATML3MBTL1
SCHEMBL14416318 0.88 KDM4E (0.53) KDM4EATML3MBTL1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017052138-A2 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2017-03-30 WO disclosed