Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 14/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957332 | 1.00 | UTS2R (0.46) | UTS2RL3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL1869071 | 1.00 | UTS2R (0.46) | UTS2RL3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL16374881 | 0.89 | KMT2A (0.47) | UTS2RL3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL960035 | 0.88 | SMN1; SMN2 (0.45) | L3MBTL1KMT2AMEN1MAPTHPGD | |
| SCHEMBL958265 | 0.78 | UTS2R (0.39) | UTS2RL3MBTL1KMT2AMEN1 | |
| SCHEMBL15163671 | 0.77 | UTS2R (0.38) | UTS2R | |
| SCHEMBL15163670 | 0.77 | UTS2R (0.38) | UTS2R | |
| SCHEMBL958625 | 0.77 | UTS2R (0.38) | UTS2R | |
| SCHEMBL3655073 | 0.76 | KMT2A (0.39) | KMT2AMEN1MAPTHPGD | |
| SCHEMBL3655071 | 0.76 | KMT2A (0.39) | KMT2AMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324017-A2 | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 | Boehringer Ingelheim International GmbH (DE) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010010157-A2 | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-28 | — | — | WO | disclosed |