Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.82 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701445 | 0.90 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1868297 | 0.87 | BCL2 (0.81) | BCL2BCL2L1 | |
| SCHEMBL30313849 | 0.85 | BCL2 (0.90) | BCL2 | |
| SCHEMBL1701545 | 0.85 | BCL2 (0.90) | BCL2 | |
| SCHEMBL1699827 | 0.82 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL8538394 | 0.81 | BCL2 (0.71) | BCL2BCL2L1 | |
| SCHEMBL1957594 | 0.81 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1701566 | 0.80 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL31344618 | 0.80 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL16638138 | 0.79 | BCL2 (0.79) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138588-A9 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | WO | disclosed |