Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.57 |
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.57 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20282926 | 0.92 | KLKB1 (0.57) | KLKB1MAP4K1MASP2F7F3 | |
| SCHEMBL21064331 | 0.80 | KLKB1 (0.45) | KLKB1MAP4K1 | |
| SCHEMBL18458339 | 0.80 | KLKB1 (0.45) | KLKB1MAP4K1 | |
| SCHEMBL18697232 | 0.80 | KLKB1 (0.55) | KLKB1MAP4K1 | |
| SCHEMBL18458981 | 0.80 | KLKB1 (0.44) | KLKB1MAP4K1 | |
| SCHEMBL20616378 | 0.79 | KLKB1 (0.55) | KLKB1MAP4K1 | |
| SCHEMBL21064317 | 0.78 | KLKB1 (0.55) | KLKB1MAP4K1 | |
| SCHEMBL18458953 | 0.77 | KLKB1 (0.45) | KLKB1MAP4K1 | |
| SCHEMBL21064315 | 0.76 | KLKB1 (0.57) | KLKB1MAP4K1 | |
| SCHEMBL18697222 | 0.76 | KLKB1 (0.38) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611252-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2017-04-04 | — | — | US | disclosed |