Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | CD38 | P28907 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697211 | 0.83 | KLKB1 (0.39) | KLKB1 | |
| SCHEMBL18458953 | 0.81 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL20616373 | 0.80 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL23279872 | 0.79 | KLKB1 (0.40) | PARP1KLKB1 | |
| SCHEMBL17447329 | 0.76 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL18459038 | 0.76 | KLKB1 (0.41) | KLKB1 | |
| SCHEMBL17442701 | 0.76 | KLKB1 (0.53) | KLKB1 | |
| SCHEMBL20282946 | 0.71 | KLKB1 (0.36) | KLKB1 | |
| SCHEMBL21064331 | 0.71 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL17442728 | 0.69 | KLKB1 (0.56) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611252-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2017-04-04 | — | — | US | disclosed |