Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADK | P55263 | 2/20 | 0.30 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | ROS1 | P08922 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148585 | 0.89 | ADORA2A (0.32) | ADORA2A | |
| SCHEMBL881381 | 0.88 | ADORA2A (0.40) | ADORA2AADORA3ADKDOT1L | |
| SCHEMBL10149698 | 0.88 | ADORA2A (0.40) | ADORA2AADORA3ADKDOT1L | |
| SCHEMBL19229288 | 0.76 | ADORA2A (0.35) | ADORA2AADORA3ADKDOT1LDCLK1 | |
| SCHEMBL19229334 | 0.76 | ADORA2A (0.35) | ADORA2AADORA3ADKDOT1LDCLK1 | |
| SCHEMBL15682919 | 0.76 | ADORA2A (0.41) | ADORA2AADORA3ADKDOT1L | |
| SCHEMBL882508 | 0.76 | ADORA2A (0.35) | ADORA2AADORA3ADK | |
| SCHEMBL10186054 | 0.76 | ADORA2A (0.35) | ADORA2AADORA3ADK | |
| SCHEMBL881487 | 0.75 | ADORA2A (0.38) | ADORA2AADORA3ADKDOT1L | |
| SCHEMBL10148675 | 0.75 | PDE4D (0.33) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150608-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | Gilead Sciences, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |