SCHEMBL18698199

SCHEMBL18698199

N#Cc1ccc(-c2cccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6c7ccccc7c7ccccc7c6c5)ccc43)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PTGER4 P35408 1/20 0.37
PGR P06401 1/20 0.36
RORC P51449 6/20 0.35
PDPK1 O15530 1/20 0.34
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
TSPO P30536 1/20 0.33
USP14 P54578 1/20 0.33
CFD P00746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20616921 0.98 ATM (0.42) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL17034464 0.95 KDM4E (0.37) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL17032723 0.94 KDM4E (0.36) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL15250654 0.94 KDM4E (0.44) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18623541 0.94 KDM4E (0.44) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18698248 0.94 KDM4E (0.40) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL17034476 0.93 KDM4E (0.39) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL21984920 0.93 ATM (0.46) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL21984906 0.93 ATM (0.46) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18698249 0.93 ATM (0.46) KDM4EATML3MBTL1PTGER4PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569605-A1 NOVEL ELECTROLUMINESCENT METAL COMPLEXES AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2019-11-20 EP disclosed
EP-3150606-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLES CARRYING BENZOFURANE OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2019-08-14 EP disclosed
US-20190006601-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICES CONTAINING THEM IDEMITSU KOSAN CO., LTD. (JP) 2019-01-03 US disclosed
EP-3150604-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2017-04-05 EP disclosed
EP-3150606-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLES CARRYING BENZOFURANE OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2017-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190006601-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICES CONTAINING THEM SLC39A11, S100A11, SLC29A1 KDM4E 4125/4885ATM 3977/4885L3MBTL1 3116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.