Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.76 |
| ▸ | EGFR | P00533 | 7/20 | 0.76 |
| ▸ | SRC | P12931 | 3/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18700071 | 1.00 | BTK (0.76) | BTKEGFRSRC | |
| SCHEMBL18700225 | 0.93 | BTK (0.75) | BTKEGFRSRC | |
| SCHEMBL16336629 | 0.89 | BTK (0.82) | BTKEGFRSRC | |
| SCHEMBL18600659 | 0.89 | BTK (0.82) | BTKEGFRSRC | |
| SCHEMBL17430811 | 0.89 | BTK (0.75) | BTKEGFRSRC | |
| SCHEMBL15757077 | 0.87 | BTK (0.74) | BTKEGFRSRC | |
| SCHEMBL19997537 | 0.87 | BTK (0.79) | BTKEGFRSRC | |
| SCHEMBL15472582 | 0.86 | BTK (1.00) | BTKEGFRSRC | |
| SCHEMBL15756482 | 0.86 | BTK (1.00) | BTKEGFRSRC | |
| SCHEMBL15669774 | 0.86 | BTK (1.00) | BTKEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914586-B1 | BRUTON'S TYROSINE KINASE INHIBITORS | PFIZER (US) | 2017-04-05 | — | — | EP | disclosed |