SCHEMBL187007

SCHEMBL187007

CC(=O)Cc1ccccc1Cc1c(O)c2ccccc2oc1=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 6/20 0.67
MEN1 O00255 1/20 0.67
ABCB11 O95342 1/20 0.67
ALDH1A1 P00352 1/20 0.67
LMNA P02545 1/20 0.67
TP53 P04637 1/20 0.67
CYP1A2 P05177 1/20 0.67
CYP3A4 P08684 1/20 0.67
CYP2C9 P11712 1/20 0.67
TSHR P16473 1/20 0.67
MAPK1 P28482 1/20 0.67
CYP2C19 P33261 1/20 0.67
KMT2A Q03164 1/20 0.67
PDE4D Q08499 1/20 0.67
PCSK7 Q16549 1/20 0.67
GPR35 Q9HC97 1/20 0.67
VKORC1 Q9BQB6 7/20 0.58
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
CA12 O43570 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6141726 0.82 NQO1 (0.72) NQO1MEN1ABCB11ALDH1A1LMNA
SCHEMBL7406496 0.82 NQO1 (0.77) NQO1MEN1ABCB11ALDH1A1LMNA
Dicumarol SCHEMBL33891 0.81 NQO1 (1.00) NQO1MEN1ABCB11ALDH1A1LMNA
Dicumarol SCHEMBL7454901 0.81 NQO1 (1.00) NQO1MEN1ABCB11ALDH1A1LMNA
Dicumarol SCHEMBL29703314 0.81 NQO1 (1.00) NQO1MEN1ABCB11ALDH1A1LMNA
SCHEMBL16040590 0.81 NQO1 (0.67) NQO1MEN1ABCB11ALDH1A1LMNA
SCHEMBL1649903 0.81 NQO1 (0.65) NQO1MEN1ABCB11ALDH1A1LMNA
SCHEMBL1647624 0.80 NQO1 (0.68) NQO1MEN1ABCB11ALDH1A1LMNA
SCHEMBL1648033 0.80 NQO1 (0.71) NQO1MEN1ABCB11ALDH1A1LMNA
Dicumarol SCHEMBL17927706 0.80 NQO1 (0.96) NQO1MEN1ABCB11ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7482162-B2 Determination of vitamin D metabolite and displacement from plasma or serum binding proteins IMMUNODIAGNOSTIC SYSTEMS LTD. (GB) 2009-01-27 US claimed
EP-1352238-B1 METHOD FOR DETECTION OF VITAMIN D METABOLITES IMMUNODIAGNOSTIC SYSTEMS LTD (GB) 2006-06-07 EP claimed
US-20040096900-A1 Separation vitamin d from protein; measurement; calibration; competitive binding; immunoassay IMMUNODIAGNOSTIC SYSTEMS LTD. (GB) 2004-05-20 US claimed
EP-1352238-A2 METHOD FOR DETECTION OF VITAMIN D METABOLITES Immunodiagnostic Systems Limited (GB) 2003-10-15 EP claimed
WO-2002046746-A2 METHOD FOR DETECTION OF VITAMIN D METABOLITES IMMUNODIAGNOSTIC SYSTEMS LTD (GB) 2002-06-13 WO claimed
CN-116449031-A Methods and compositions for determining vitamin D DIAZYME 研究室有限公司 2023-07-18 CN disclosed
CN-109863406-B Method and composition for determining vitamin D DIAZYME研究室有限公司 2023-04-14 CN disclosed
US-20220365103-A1 METHODS AND COMPOSITIONS FOR ASSAYING VITAMIN D DIAZYME LABORATORIES, INC. (US) 2022-11-17 US disclosed
US-11435367-B2 Methods and kits for assaying a vitamin D moiety DIAZYME LABORATORIES, INC. (US) 2022-09-06 US disclosed
US-20220120767-A1 DEVICE FOR DETECTION OF VITAMIN D METABOLITES AFFIMEDIX, INC. 2022-04-21 US disclosed
EP-3954376-A1 METHOD FOR QUANTIFICATION OF VITAMIN D METABOLITES Affimedix, Inc. (US) 2022-02-16 EP disclosed
EP-3405198-B1 DEVICE FOR DETECTION OF VITAMIN D METABOLITES AFFIMEDIX INC (US) 2021-08-04 EP disclosed
US-20040096900-A1 Separation vitamin d from protein; measurement; calibration; competitive binding; immunoassay IMMUNODIAGNOSTIC SYSTEMS LTD. (GB) 2004-05-20 US disclosed
EP-1352238-A2 METHOD FOR DETECTION OF VITAMIN D METABOLITES Immunodiagnostic Systems Limited (GB) 2003-10-15 EP disclosed
WO-2002046746-A2 METHOD FOR DETECTION OF VITAMIN D METABOLITES IMMUNODIAGNOSTIC SYSTEMS LTD (GB) 2002-06-13 WO disclosed
EP-1066520-A1 INTERACTIONS BETWEEN SUBSTANCES AND SURFACES THAT ARE MADE UP OF AMPHIPHILIC MOLECULES Nimbus Biotechnologie Gmbh (DE) 2001-01-10 EP disclosed
WO-1999051984-A1 INTERACTIONS BETWEEN SUBSTANCES AND SURFACES THAT ARE MADE UP OF AMPHIPHILIC MOLECULES NIMBUS BIOTECHNOLOGIE GMBH (DE) 1999-10-14 WO disclosed
WO-1996024558-A1 METHOD AND APPARATUS FOR THERMAL DECOMPOSITION AND SEPARATION OF COMPONENTS WITHIN AN AQUEOUS STREAM HPR CORPORATION (US) 1996-08-15 WO disclosed
EP-0059729-A1 PLANT-DERIVED CELL AGGREGATE, PLANT GRANULATE, PRODUCTION AND USE THEREOF FULLER, Keith William (GB) 1982-09-15 EP disclosed
WO-1982001010-A1 PLANT-DERIVED CELL AGGREGATE,PLANT GRANULATE,PRODUCTION AND USE THEREOF BARTLETT D 1982-04-01 WO disclosed