Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1869091 | 0.82 | TLR7 (0.57) | TLR7 | |
| SCHEMBL1870034 | 0.82 | TLR7 (0.53) | TLR7 | |
| SCHEMBL1881384 | 0.79 | TLR7 (0.58) | TLR7 | |
| SCHEMBL1877583 | 0.78 | TLR7 (0.53) | TLR7 | |
| SCHEMBL1877586 | 0.78 | TLR7 (0.53) | TLR7 | |
| SCHEMBL1876573 | 0.76 | TLR7 (0.81) | TLR7 | |
| SCHEMBL2573444 | 0.75 | TLR7 (0.78) | TLR7 | |
| SCHEMBL563045 | 0.74 | TLR7 (0.72) | TLR7 | |
| SCHEMBL12667653 | 0.74 | TLR7 (0.48) | TLR7 | |
| SCHEMBL1874349 | 0.72 | TLR7 (0.54) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | claimed |
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | disclosed |