Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.57 |
| ▸ | PLG | P00747 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 3/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19326765 | 0.87 | FOLH1 (0.66) | FOLH1PKMHSP90AB1PRSS1PRSS2 | |
| SCHEMBL20533126 | 0.85 | FOLH1 (0.66) | FOLH1PKMHSP90AB1PRSS1PRSS2 | |
| SCHEMBL21531147 | 0.83 | FOLH1 (0.70) | FOLH1PKMHSP90AB1PRSS1PRSS2 | |
| SCHEMBL21531206 | 0.83 | FOLH1 (0.70) | FOLH1PKMHSP90AB1PRSS1PRSS2 | |
| SCHEMBL19017236 | 0.83 | F2 (0.73) | FOLH1PKMHSP90AB1PRSS1PRSS2 | |
| SCHEMBL4968230 | 0.83 | F2 (0.73) | FOLH1PKMHSP90AB1PRSS1PRSS2 | |
| SCHEMBL15216220 | 0.83 | F2 (0.73) | FOLH1PKMHSP90AB1PRSS1PRSS2 | |
| SCHEMBL19751698 | 0.83 | F2 (0.73) | FOLH1PKMHSP90AB1PRSS1PRSS2 | |
| SCHEMBL19326752 | 0.82 | FOLH1 (0.63) | FOLH1PKMHSP90AB1PRSS1PRSS2 | |
| SCHEMBL18690250 | 0.82 | FOLH1 (0.74) | FOLH1PKMHSP90AB1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060729-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTAURI THERAPEUTICS LIMITED (GB) | 2017-04-13 | — | — | WO | disclosed |