SCHEMBL187068

SCHEMBL187068

CC(=O)OC[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)OC(C)=O

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.88
ABCB1 P08183 1/20 0.51
POLB P06746 1/20 0.47
MAPK1 P28482 1/20 0.47
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TRPV1 Q8NER1 1/20 0.36
PGD P52209 1/20 0.35
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM1 P11229 2/20 0.34
TBXA2R P21731 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.33
GALR3 O60755 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15298821 1.00 TDP1 (0.88) TDP1ABCB1POLBMAPK1TSHR
SCHEMBL7154355 1.00 TDP1 (0.88) TDP1ABCB1POLBMAPK1TSHR
SCHEMBL7146329 1.00 TDP1 (0.88) TDP1ABCB1POLBMAPK1TSHR
SCHEMBL2175855 0.95 TDP1 (0.96) TDP1ABCB1POLBMAPK1TSHR
SCHEMBL7150717 0.95 TDP1 (0.96) TDP1ABCB1POLBMAPK1TSHR
SCHEMBL13168216 0.95 TDP1 (0.96) TDP1ABCB1POLBMAPK1TSHR
SCHEMBL7149374 0.95 TDP1 (0.96) TDP1ABCB1POLBMAPK1TSHR
SCHEMBL826717 0.95 TDP1 (0.96) TDP1ABCB1POLBMAPK1TSHR
SCHEMBL270042 0.95 TDP1 (0.96) TDP1ABCB1POLBMAPK1TSHR
SCHEMBL7152317 0.95 TDP1 (0.96) TDP1ABCB1POLBMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3046566-B1 METHODS AND MATERIALS FOR TREATING LIVER STEATOSIS UNIV NEW YORK STATE RES FOUND (US) 2020-12-02 EP claimed
EP-2834255-B1 METHODS AND MATERIALS RELATED TO NUTRITIONAL SUPPLEMENT COMPOSITIONS CONTAINING A POTATO POLYSACCHARIDE PREPARATION UNIV NEW YORK STATE RES FOUND (US) 2020-11-04 EP claimed
EP-2401303-B1 MIXED CELLULOSE ESTER FILMS HAVING +C PLATE AND -A PLATE OPTICAL PROPERTIES EASTMAN CHEM CO (US) 2019-09-04 EP claimed
CN-103597015-B Cellulose triacetate films with low birefringence 伊士曼化工公司 2016-08-17 CN claimed
EP-2721096-B1 CELLULOSE TRIACETATE FILMS WITH LOW BIREFRINGENCE EASTMAN CHEM CO (US) 2016-05-18 EP claimed
EP-2185635-B1 MIXED CELLULOSE ESTER COMPOSITIONS COMPRISING A PLASTICIZER AND HAVING LOW BIFRINGENCE AND FILMS MADE THEREFROM FOR LIQUID CRYSTAL DISPLAYS EASTMAN CHEM CO (US) 2016-03-30 EP claimed
US-20140168770-A1 MULTILAYER AND SINGLE LAYER CELLULOSE ESTER FILMS HAVING REVERSED OPTICAL DISPERSION EASTMAN CHEMICAL COMPANY (US) 2014-06-19 US claimed
US-8735572-B2 Cellulose ester compositions having low birefringence and films made therefrom comprising a plasticizer EASTMAN CHEMICAL COMPANY (US) 2014-05-27 US claimed
EP-2721096-A1 CELLULOSE TRIACETATE FILMS WITH LOW BIREFRINGENCE Eastman Chemical Company (US) 2014-04-23 EP claimed
US-8349921-B2 Mixed cellulose ester films having +C plate and −A plate optical properties EASTMAN CHEMICAL COMPANY (US) 2013-01-08 US claimed
US-20120320313-A1 CELLULOSE TRIACETATE FILMS WITH LOW BIREFRINGENCE EASTMAN CHEMICAL COMPANY (US) 2012-12-20 US claimed
WO-2012173879-A1 CELLULOSE TRIACETATE FILMS WITH LOW BIREFRINGENCE EASTMAN CHEMICAL COMPANY (US) 2012-12-20 WO claimed
EP-2401303-A1 MIXED CELLULOSE ESTER FILMS HAVING +C PLATE AND -A PLATE OPTICAL PROPERTIES Eastman Chemical Company (US) 2012-01-04 EP claimed
JP-2010536994-A 2010-12-02 JP claimed
WO-2010098816-A1 MIXED CELLULOSE ESTER FILMS HAVING +C PLATE AND -A PLATE OPTICAL PROPERTIES EASTMAN CHEMICAL COMPANY (US) 2010-09-02 WO claimed
EP-2185635-A1 MIXED CELLULOSE ESTER COMPOSITIONS COMPRISING A PLASTICIZER AND HAVING LOW BIFRINGENCE AND FILMS MADE THEREFROM FOR LIQUID CRYSTAL DISPLAYS Eastman Chemical Company (US) 2010-05-19 EP claimed
US-20100089288-A1 CELLULOSE ESTER COMPOSITIONS HAVING LOW BIFRINGENCE AND FILMS MADE THEREFROM COMPRISING A PLASTICIZER EASTMAN CHEMICAL COMPANY (US) 2010-04-15 US claimed
US-20090181232-A1 MIXED CELLULOSE ESTER FILMS HAVING +C PLATE AND -A PLATE OPTICAL PROPERTIES EASTMAN CHEMICAL COMPANY (US) 2009-07-16 US claimed
WO-2009029217-A1 MIXED CELLULOSE ESTER COMPOSITIONS COMPRISING A PLASTICIZER AND HAVING LOW BIFRINGENCE AND FILMS MADE THEREFROM FOR LIQUID CRYSTAL DISPLAYS EASTMAN CHEMICAL COMPANY (US) 2009-03-05 WO claimed
US-20090050842-A1 Cellulose Ester Compositions Having Low Bifringence and Films Made Therefrom Comprising a Plasticizer EASTMAN CHEMICAL COMPANY (US) 2009-02-26 US claimed