Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503737 | 1.00 | ABL1 (0.36) | ABL1RIN1POLBHTTALDH1A1 | |
| SCHEMBL26621810 | 0.97 | ABL1 (0.35) | ABL1RIN1POLBHTTALDH1A1 | |
| SCHEMBL18708175 | 0.88 | ABL1 (0.39) | ABL1RIN1POLBHTTALDH1A1 | |
| SCHEMBL18503738 | 0.88 | ABL1 (0.39) | ABL1RIN1POLBHTTALDH1A1 | |
| SCHEMBL26621808 | 0.84 | ABL1 (0.38) | ABL1RIN1POLBHTTALDH1A1 | |
| SCHEMBL18708173 | 0.84 | ABL1 (0.32) | ABL1RIN1 | |
| SCHEMBL18503734 | 0.84 | ABL1 (0.32) | ABL1RIN1 | |
| SCHEMBL18513393 | 0.82 | ABL1 (0.41) | ABL1RIN1POLBHTTALDH1A1 | |
| SCHEMBL18503730 | 0.79 | — | — | |
| SCHEMBL26621807 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611479-B2 | Crosslinked nucleoside and nucleotide | OSAKA UNIVERSITY (JP) | 2017-04-04 | — | — | US | disclosed |