Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218369 | 0.83 | ADORA2A (0.41) | PIK3CDPIK3R1ADORA2AADORA1CHUK | |
| SCHEMBL250961 | 0.82 | PIK3CD (0.41) | PIK3CDPIK3R1ADORA2AADORA1CHUK | |
| SCHEMBL217591 | 0.82 | PIK3CD (0.41) | PIK3CDPIK3R1ADORA2AADORA1CHUK | |
| SCHEMBL251804 | 0.82 | PIK3CD (0.41) | PIK3CDPIK3R1ADORA2AADORA1CHUK | |
| SCHEMBL21389720 | 0.80 | PIK3CD (0.40) | PIK3CDPIK3R1ADORA2AADORA1CHUK | |
| SCHEMBL179438 | 0.78 | PIK3CD (0.38) | PIK3CDPIK3R1ADORA2AADORA1CHUK | |
| SCHEMBL179466 | 0.78 | PIK3CD (0.38) | PIK3CDPIK3R1ADORA2AADORA1CHUK | |
| SCHEMBL179430 | 0.78 | PIK3CD (0.38) | PIK3CDPIK3R1ADORA2AADORA1CHUK | |
| SCHEMBL15354452 | 0.78 | LRRK2 (0.47) | PIK3CDPIK3R1ADORA2AADORA1CHUK | |
| SCHEMBL12692538 | 0.77 | PIK3CD (0.37) | PIK3CDPIK3R1ADORA2AADORA1CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150609-A1 | PROCESS FOR PREPARING CERTAIN CHEMICAL ENTITIES | Intellikine, LLC (US) | 2017-04-05 | — | — | EP | disclosed |