Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16290717 | 1.00 | CA1 (0.46) | CA1CA2KMT2ATDP1CYP2C8 | |
| SCHEMBL16290339 | 0.88 | CA1 (0.42) | CA1CA2KMT2ATDP1CYP2C8 | |
| SCHEMBL16307305 | 0.88 | CA1 (0.42) | CA1CA2KMT2ATDP1CYP11B1 | |
| SCHEMBL16307314 | 0.88 | CA1 (0.42) | CA1CA2KMT2ATDP1CYP2C8 | |
| SCHEMBL16307315 | 0.88 | CA1 (0.42) | CA1CA2KMT2ATDP1CYP2C8 | |
| SCHEMBL16290393 | 0.88 | CA1 (0.42) | CA1CA2KMT2ATDP1CYP2C8 | |
| SCHEMBL16290406 | 0.88 | CA1 (0.42) | CA1CA2KMT2ATDP1CYP11B1 | |
| SCHEMBL16307317 | 0.88 | CA1 (0.42) | CA1CA2KMT2ATDP1CYP2C8 | |
| SCHEMBL16290386 | 0.81 | CA1 (0.44) | CA1CA2 | |
| SCHEMBL16307316 | 0.81 | CA1 (0.44) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2865663-B1 | NOVEL INDANESULFAMIDE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2017-04-05 | — | — | EP | disclosed |