Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3013865 | 0.92 | KMT2A (0.41) | CACNA1BAPBA1SAE1UBA2KMT2A | |
| SCHEMBL3002056 | 0.84 | KMT2A (0.53) | CACNA1BAPBA1SAE1UBA2KMT2A | |
| SCHEMBL13984508 | 0.76 | KMT2A (0.56) | KMT2AMAPK1SMN1; SMN2LMNAMAPT | |
| SCHEMBL13245364 | 0.74 | KMT2A (0.54) | CACNA1BAPBA1SAE1UBA2KMT2A | |
| SCHEMBL3013062 | 0.73 | KMT2A (0.47) | CACNA1BAPBA1SAE1UBA2KMT2A | |
| SCHEMBL3022019 | 0.73 | CACNA1B (0.46) | CACNA1BAPBA1SAE1UBA2L3MBTL1 | |
| SCHEMBL3022024 | 0.73 | CACNA1B (0.46) | CACNA1BAPBA1SAE1UBA2L3MBTL1 | |
| SCHEMBL13244990 | 0.72 | KMT2A (0.53) | CACNA1BAPBA1SAE1UBA2KMT2A | |
| SCHEMBL3012858 | 0.72 | — | — | |
| SCHEMBL13245463 | 0.72 | KMT2A (0.52) | CACNA1BAPBA1SAE1UBA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |