Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18715459 | 0.90 | MAP3K5 (0.81) | MAP3K5AKT1 | |
| SCHEMBL18715426 | 0.89 | MAP3K5 (0.81) | MAP3K5AKT1 | |
| SCHEMBL15811891 | 0.89 | MAP3K5 (1.00) | MAP3K5AKT1 | |
| SCHEMBL15811890 | 0.89 | MAP3K5 (1.00) | MAP3K5AKT1 | |
| SCHEMBL18715415 | 0.88 | MAP3K5 (0.81) | MAP3K5AKT1 | |
| SCHEMBL20902658 | 0.88 | MAP3K5 (0.80) | MAP3K5AKT1 | |
| SCHEMBL18715395 | 0.87 | MAP3K5 (0.81) | MAP3K5AKT1 | |
| SCHEMBL15835598 | 0.87 | MAP3K5 (0.91) | MAP3K5AKT1 | |
| SCHEMBL18715550 | 0.87 | MAP3K5 (0.81) | MAP3K5AKT1 | |
| SCHEMBL20902690 | 0.86 | MAP3K5 (0.82) | MAP3K5AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150597-A1 | SUBSTITUTED PYRIDINE-2-CARBOXAMIDE COMPOUNDS AS APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |