SCHEMBL18716624

SCHEMBL18716624

C=C(CN1C2CCC1CC(CNC(=O)c1coc3ccccc13)C2)NC(C)(C)C

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CACNA1H O95180 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18686543 0.91 CACNA1H (1.00) CACNA1H
SCHEMBL18686578 0.91 CACNA1H (1.00) CACNA1H
SCHEMBL18686545 0.91 CACNA1H (1.00) CACNA1H
SCHEMBL19063572 0.85 CACNA1H (0.83) CACNA1H
SCHEMBL18686664 0.85 CACNA1H (0.83) CACNA1H
SCHEMBL18686468 0.85 CACNA1H (0.77) CACNA1H
SCHEMBL18686471 0.85 CACNA1H (0.77) CACNA1H
SCHEMBL19092153 0.85 CACNA1H (0.77) CACNA1H
SCHEMBL18686622 0.85 CACNA1H (0.85) CACNA1H
SCHEMBL18686619 0.85 CACNA1H (0.85) CACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3150598-B1 SUBSTITUTED TROPANE DERIVATIVES TOA EIYO LTD (JP) 2019-02-13 EP disclosed
EP-3150598-A1 SUBSTITUTED TROPANE DERIVATIVES TOA Eiyo Ltd. (JP) 2017-04-05 EP disclosed