SCHEMBL18716637

SCHEMBL18716637

CC(C)(CO)NC(=O)CN1[C@@H]2CC[C@H]1CC(CNC(=O)C13CC4CC(CC1C4)C3)C2

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CACNA1H O95180 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082653 1.00 CACNA1H (0.64) CACNA1H
SCHEMBL19092157 0.91 CACNA1H (0.78) CACNA1H
SCHEMBL19082662 0.91 CACNA1H (0.78) CACNA1H
SCHEMBL18716650 0.91 CACNA1H (0.78) CACNA1H
SCHEMBL19082654 0.91 CACNA1H (0.78) CACNA1H
SCHEMBL19092176 0.91 CACNA1H (0.78) CACNA1H
SCHEMBL19082655 0.80 CACNA1H (0.79) CACNA1H
SCHEMBL19082637 0.78 CACNA1H (1.00) CACNA1H
SCHEMBL18686511 0.78 CACNA1H (1.00) CACNA1H
SCHEMBL18686512 0.78 CACNA1H (1.00) CACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3150598-B1 SUBSTITUTED TROPANE DERIVATIVES TOA EIYO LTD (JP) 2019-02-13 EP disclosed
EP-3150598-A1 SUBSTITUTED TROPANE DERIVATIVES TOA Eiyo Ltd. (JP) 2017-04-05 EP disclosed