Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 0.59 |
| ▸ | MC5R | P33032 | 5/20 | 0.55 |
| ▸ | MC3R | P41968 | 5/20 | 0.55 |
| ▸ | MC1R | Q01726 | 5/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18716878 | 0.96 | MC4R (0.58) | MC4RMC5RMC3RMC1RTUBB4A | |
| SCHEMBL18717028 | 0.96 | MC4R (0.61) | MC4RMC5RMC3RMC1RTUBB4A | |
| SCHEMBL18716879 | 0.95 | MC4R (0.63) | MC4RMC5RMC3RMC1RTUBB4A | |
| SCHEMBL10089224 | 0.95 | MC4R (0.63) | MC4RMC5RMC3RMC1RTUBB4A | |
| SCHEMBL7860265 | 0.95 | MC4R (0.63) | MC4RMC5RMC3RMC1RTUBB4A | |
| SCHEMBL18716919 | 0.93 | MC4R (0.59) | MC4RMC5RMC3RMC1RTUBB4A | |
| SCHEMBL10089242 | 0.93 | MC4R (0.60) | MC4RMC5RMC3RMC1RTUBB4A | |
| SCHEMBL7855343 | 0.93 | MC4R (0.60) | MC4RMC5RMC3RMC1RTUBB4A | |
| SCHEMBL18717067 | 0.93 | MC4R (0.64) | MC4RMC5RMC3RMC1RTUBB4A | |
| SCHEMBL18717060 | 0.93 | MC4R (0.64) | MC4RMC5RMC3RMC1RTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440572-B1 | LACTAM-BRIDGED MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | PALATIN TECHNOLOGIES INC (US) | 2017-04-05 | — | — | EP | disclosed |