Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 6/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5018772 | 0.92 | HTR2A (0.48) | HTR2AHTR2BHTR2CIDO1SIGMAR1 | |
| SCHEMBL26464609 | 0.81 | IDO1 (0.39) | HTR2AHTR2BHTR2CIDO1TACR1 | |
| SCHEMBL22861021 | 0.81 | HTR2A (0.43) | HTR2AHTR2BHTR2CIDO1SIGMAR1 | |
| SCHEMBL13400797 | 0.81 | HTR2A (0.43) | HTR2AHTR2BHTR2CIDO1SIGMAR1 | |
| SCHEMBL8244696 | 0.81 | HTR2A (0.43) | HTR2AHTR2BHTR2CIDO1SIGMAR1 | |
| SCHEMBL16956639 | 0.80 | HTR2A (0.40) | HTR2AHTR2BHTR2CIDO1SIGMAR1 | |
| SCHEMBL6814904 | 0.79 | HTR2A (0.46) | HTR2AHTR2BHTR2CIDO1SIGMAR1 | |
| SCHEMBL16955182 | 0.79 | HTR2A (0.42) | HTR2AHTR2BHTR2CIDO1SIGMAR1 | |
| SCHEMBL16960837 | 0.79 | HTR2A (0.42) | HTR2AHTR2BHTR2CIDO1SIGMAR1 | |
| SCHEMBL13434209 | 0.79 | HTR2A (0.42) | HTR2AHTR2BHTR2CIDO1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101369-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS STAT5 INHIBITORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101369-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS STAT5 INHIBITORS | STAT5A, STAT5B, JAK2 | HTR2A 4018/4885HTR2B 3418/4885HTR2C 3998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.