Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 19/20 | 0.56 |
| ▸ | ACE | P12821 | 6/20 | 0.50 |
| ▸ | EMG1 | Q92979 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17011183 | 1.00 | MME (0.56) | MMEACEEMG1 | |
| SCHEMBL17011184 | 0.93 | MME (0.60) | MMEACE | |
| SCHEMBL19825624 | 0.92 | MME (0.57) | MMEACEEMG1 | |
| SCHEMBL17011185 | 0.92 | MME (0.57) | MMEACEEMG1 | |
| SCHEMBL19825625 | 0.91 | MME (0.67) | MMEACE | |
| SCHEMBL18724689 | 0.91 | MME (0.67) | MMEACE | |
| SCHEMBL9930240 | 0.91 | MME (0.67) | MMEACE | |
| SCHEMBL17011182 | 0.89 | MME (0.51) | MMEACEEMG1 | |
| SCHEMBL17011369 | 0.88 | MME (0.50) | MMEACE | |
| SCHEMBL18724763 | 0.88 | MME (0.50) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864292-B1 | NEPRILYSIN INHIBITORS | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2017-04-12 | — | — | EP | disclosed |