Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.76 |
| ▸ | KLK1 | P06870 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725275 | 0.91 | KLKB1 (0.78) | KLKB1 | |
| SCHEMBL18725251 | 0.91 | KLKB1 (0.78) | KLKB1KLK1 | |
| SCHEMBL18725225 | 0.84 | KLKB1 (0.77) | KLKB1 | |
| SCHEMBL18725246 | 0.82 | KLKB1 (0.77) | KLKB1 | |
| SCHEMBL18725250 | 0.82 | KLKB1 (0.77) | KLKB1 | |
| SCHEMBL18725219 | 0.82 | KLKB1 (0.78) | KLKB1 | |
| SCHEMBL18725283 | 0.82 | KLKB1 (0.79) | KLKB1KLK1 | |
| SCHEMBL18725253 | 0.82 | KLKB1 (0.79) | KLKB1KLK1 | |
| SCHEMBL18725260 | 0.81 | KLKB1 (0.79) | KLKB1KLK1 | |
| SCHEMBL18725229 | 0.81 | KLKB1 (0.75) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999697-B1 | HETEROCYCLIC DERIVATES | KALVISTA PHARMACEUTICALS LTD (GB) | 2017-04-19 | — | — | EP | claimed |