Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18731911 | 1.00 | GPBAR1 (0.45) | GPBAR1NR1H4CDC25ACDC25BAKR1B10 | |
| SCHEMBL19194725 | 0.88 | GPBAR1 (0.60) | GPBAR1NR1H4AKR1B10AKR1B1EFNA1 | |
| SCHEMBL6559019 | 0.80 | CDC25A (0.62) | CDC25ACDC25BMEN1LMNAKMT2A | |
| SCHEMBL18732190 | 0.78 | UGT2B7 (0.38) | NR1H4 | |
| SCHEMBL18200025 | 0.78 | NR1H4 (0.55) | GPBAR1NR1H4 | |
| SCHEMBL17303340 | 0.78 | GPBAR1 (0.57) | GPBAR1NR1H4AKR1B10AKR1B1EFNA1 | |
| SCHEMBL17303336 | 0.76 | GPBAR1 (0.55) | GPBAR1NR1H4AKR1B10AKR1B1EFNA1 | |
| SCHEMBL18199998 | 0.75 | NR1H4 (0.60) | NR1H4 | |
| SCHEMBL25071391 | 0.73 | GPBAR1 (0.77) | GPBAR1NR1H4 | |
| SCHEMBL17303303 | 0.73 | GPBAR1 (0.77) | GPBAR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017062763-A1 | FARNESOID X RECEPTOR MODULATORS | INTERCEPT PHARMACEUTICALS, INC. (US) | 2017-04-13 | — | — | WO | disclosed |