SCHEMBL18735710

SCHEMBL18735710

NN[C@@H](CCCCNC(=O)CC[C@H](NC(=O)CCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)C(N)=O

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.66
▸ CCKAR P32238 8/20 0.46
▸ CCKBR P32239 8/20 0.46
▸ NOD1 Q9Y239 1/20 0.45
▸ FOLH1 Q04609 2/20 0.44
▸ GNPAT O15228 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17401200 0.99 GLP1R (0.67) GLP1RCCKARCCKBRFOLH1GNPAT
SCHEMBL19786830 0.99 GLP1R (0.67) GLP1RCCKARCCKBRFOLH1GNPAT
SCHEMBL21099643 0.98 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL16192883 0.98 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL21099692 0.98 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL16192882 0.98 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL19307987 0.98 GLP1R (0.66) GLP1RCCKARCCKBR
SCHEMBL19867142 0.97 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1GNPAT
SCHEMBL21099861 0.97 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1GNPAT
SCHEMBL16192886 0.97 GLP1R (0.65) GLP1RCCKARCCKBRFOLH1GNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10570184-B2 GLP-1/glucagon receptor co-agonists for medical use NOVO NORDISK A/S (DK) 2020-02-25 — — US disclosed
US-20170101454-A1 GLP-1/Glucagon Receptor Co-Agonists for Medical Use NOVO NORDISK A/S (DK) 2017-04-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170101454-A1 GLP-1/Glucagon Receptor Co-Agonists for Medical Use GLP1R, GCGR, GIPR GLP1R 1/4885CCKAR 28/4885CCKBR 31/4885
US-10570184-B2 GLP-1/glucagon receptor co-agonists for medical use GLP1R, GCGR, GIPR GLP1R 1/4885CCKAR 26/4885CCKBR 31/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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