⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10304335 | 0.89 | — | — | |
| SCHEMBL21014898 | 0.89 | — | — | |
| SCHEMBL18629412 | 0.89 | — | — | |
| SCHEMBL10007203 | 0.89 | CDC7 (0.44) | — | |
| SCHEMBL10304332 | 0.87 | — | — | |
| SCHEMBL16015244 | 0.85 | — | — | |
| SCHEMBL10304354 | 0.82 | — | — | |
| SCHEMBL10304242 | 0.81 | CDC7 (0.47) | — | |
| SCHEMBL18629031 | 0.81 | — | — | |
| SCHEMBL10007187 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808459-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170100400-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED | 2017-04-13 | — | — | US | disclosed |