Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 17/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | KHK | P50053 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18692344 | 0.92 | CFTR (0.58) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692211 | 0.87 | CFTR (0.75) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692512 | 0.86 | CFTR (0.60) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18693424 | 0.86 | CFTR (0.59) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692987 | 0.86 | CFTR (0.59) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18693635 | 0.85 | CFTR (0.59) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18693127 | 0.85 | CFTR (0.60) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692718 | 0.85 | CFTR (0.68) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692434 | 0.85 | CFTR (0.60) | CFTRCYP2C9HRH1TMEM97SIGMAR1 | |
| SCHEMBL18692106 | 0.85 | CFTR (0.79) | CFTRCYP2C9HRH1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060873-A1 | SUBSTITUTED PYRAZOLO[3,4-B]PYRIDIN-6-CARBOXYLIC ACIDS AND THEIR USE | AbbVie S.à.r.l. (LU) | 2017-04-13 | — | — | WO | disclosed |