Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 16/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18694241 | 0.88 | CFTR (0.88) | CFTR | |
| SCHEMBL18694351 | 0.85 | CFTR (0.74) | CFTRKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL18694400 | 0.82 | CFTR (1.00) | CFTR | |
| SCHEMBL18694338 | 0.80 | CFTR (0.84) | CFTR | |
| SCHEMBL18694143 | 0.78 | CFTR (0.82) | CFTR | |
| SCHEMBL18704434 | 0.78 | CFTR (0.63) | CFTRKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL18694185 | 0.76 | CFTR (0.69) | CFTRKDM4EALDH1A1 | |
| SCHEMBL18692158 | 0.74 | CFTR (0.74) | CFTR | |
| SCHEMBL18693046 | 0.71 | CFTR (0.72) | CFTR | |
| SCHEMBL18694649 | 0.71 | CFTR (0.80) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060873-A1 | SUBSTITUTED PYRAZOLO[3,4-B]PYRIDIN-6-CARBOXYLIC ACIDS AND THEIR USE | AbbVie S.à.r.l. (LU) | 2017-04-13 | — | — | WO | disclosed |